HIV-1 Protease Inhibitors Based on Acyclic Carbohydrates
1998; American Chemical Society; Volume: 63; Issue: 15 Linguagem: Inglês
10.1021/jo971562c
ISSN1520-6904
AutoresGuido Zuccarello, Abderrahim Bouzide, Ingemar Kvarnström, Gunilla Niklasson, S. Svensson, Magnus Brisander, Helena Danielsson, Ulrika Nillroth, Anders Karlén, Anders Hallberg, Björn Classon, Bertil Samuelsson,
Tópico(s)HIV Research and Treatment
ResumoA series of acyclic C2-symmetric HIV protease inhibitors readily accessible from d-mannitol have been developed. Several of the compounds synthesized showed significant in vitro activity against HIV-1 protease.
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