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Chemical library synthesis using convergent approaches

2005; Elsevier BV; Volume: 9; Issue: 3 Linguagem: Inglês

10.1016/j.cbpa.2005.04.005

1879-0402

Aaron B. Beeler, Scott E. Schaus, John A. Porco,

Click Chemistry and Applications

New strategies are continuously being developed in combinatorial and diversity-oriented synthesis. Convergent design in target-oriented synthesis is commonly employed for construction of complex molecules. In this mini-review, we describe examples of convergent library design and synthesis as well as potential areas for future development.