Opening of cyclopropyl ketones with SmI2. Synthesis of spirocyclic and bicyclic ketones by intramolecular trapping of an electrophile
1997; Elsevier BV; Volume: 53; Issue: 24 Linguagem: Inglês
10.1016/s0040-4020(97)00499-7
ISSN1464-5416
AutoresGary A. Molander, Cristina Alonso‐Alija,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoA method for the opening of cyclopropyl ketones with samarium(II) iodide followed by the intramolecular trapping of an electrophile is described. This process leads to the obtainment of functionalized spirocyclic, bicyclic, and tricyclic ketones in moderate to good yields.
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