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Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium

2019; American Society for Microbiology; Volume: 87; Issue: 4 Linguagem: Inglês

10.1128/iai.00323-18

1098-5522

N. Kannan, Yi-Pin Lai, Markus Haug, M. K. Lilleness, Siril S. Bakke, Anne Marstad, Håkon Hov, Thor Naustdal, Jan Egil Afset, Thomas R. Ioerger, Trude H. Flo, Magnus Steigedal,

Gut microbiota and health

Members of the Mycobacterium avium complex (MAC) are characterized as nontuberculosis mycobacteria and are pathogenic mainly in immunocompromised individuals. MAC strains show a wide genetic variability, and there is growing evidence suggesting that genetic differences may contribute to a varied immune response that may impact the infection outcome.