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Transition Metal-Catalyzed C–C Bond Formation Reactions Using Alkyl Halides

2006; Oxford University Press; Volume: 79; Issue: 5 Linguagem: Inglês

10.1246/bcsj.79.663

1348-0634

Jun Terao, Nobuaki Kambe,

Asymmetric Hydrogenation and Catalysis

Abstract This account reviews transition metal-catalyzed C–C bond formation reactions using alkyl halides, which have rarely been used as carbon sources in conventional transition metal-catalyzed systems. In the reactions, ate complexes formed by the reaction of transition metals with a Grignard reagent play important roles as the active catalytic species. The reactions mentioned here are mechanistically new and provide a promising methodology for the construction of carbon frameworks employing alkyl halides.