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Levantamento soroepidemiológico da frequência de Toxoplasma gondii em doadores de córnea do Banco de Olhos de Volta Redonda, RJ, Brasil]

2016; Sociedade de Medicina Veterinária do Estado do Rio de Janeiro; Volume: 38; Linguagem: Inglês

2527-2179

Mariana Gleice Seabra, Ana Luisa Quintella do Couto Aleixo, Pâmela Figueiredo Pereira, Jairo Pinheiro, Maria Regina Reis Amendoeira,

Herpesvirus Infections and Treatments

ABSTRACT. Seabra M.G., Aleixo A.L.Q. do C., Pereira P.F., Pinheiro J., Amendoeira M.R.R. [Levantamento soroepidemiologico da frequencia de Toxoplasma gondii em doadores de cornea do Banco de Olhos de Volta Redonda, RJ, Brasil] A seroepidemiological survey of the frequency of Toxoplasma gondii in corneal donors from Volta Redonda eye bank . Revista Brasileira de Medicina Veterinaria, 38(supl. 3):229-239, 2016. Programa de Pos-graduacao em Ciencias Veterinarias, Instituto de Veterinaria, Universidade Federal Rural do Rio de Janeiro, BR 465, km 7, Campus Seropedica 23897-970, Seropedica, RJ, Brazil. E-mail: jairopinheirodasilva@gmail.com Toxoplasma gondii is a protozoan parasite that infects up to a third of the world's population. Infection is mainly acquired by ingestion of food or water that is contaminated with oocysts shed by cats or by eating undercooked or raw meat containing tissue cysts and by blood transfusion or organ transplantation. Primary infection is usually subclinical but in some patients cervical lymphadenopathy or ocular disease can be present. Infection acquired during pregnancy may cause severe damage to the fetus. In immunocompromised patients, reactivation of latent disease can cause life-threatening encephalitis. Diagnosis of toxoplasmosis can be established by direct detection of the parasite or by serological techniques. The aim of the present study was verify the seroprevalence of toxoplasmosis in cornea donors of Rio de Janeiro, Brazil. IgM and IgG anti- T. gondii antibodies were investigated in 426 sera of corneal donors by using the indirect fluorescent antibody test (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. Demographic information of study subjects including their gender, age, cause of death and home region were recorded. Out of 426 serum samples, 338 (79.34%) and 17 (3.99%) were positive regarding anti-T. gondii IgG and IgM antibodies ELISA and/or IFAT, respectively. These data demonstrate the importance of regional and national seroepidemiological inquiries to define public health strategies that can revert and reduce the serological toxoplasmosis prevalence in Brazil.