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Ceric ammonium nitrate (CAN) catalyzed synthesis of N-substituted decahydroacridine-1,8-diones in PEG

2010; Elsevier BV; Volume: 51; Issue: 20 Linguagem: Inglês

10.1016/j.tetlet.2010.03.033

1873-3581

Mazaahir Kidwai, Divya Bhatnagar,

Synthesis and Biological Activity

Polyethylene glycol (PEG) was found to be an inexpensive non-toxic and effective medium for the one-pot synthesis of N-substituted decahydroacridine-1,8-diones in the presence of ceric ammonium nitrate (CAN) as the catalyst in high yields. Also, the solvent system can be recovered and reused; making this protocol economically and potentially viable.