Oxidative Carbon−Carbon Bond Formation in the Synthesis of Bioactive Spiro β-Lactams
2009; American Chemical Society; Volume: 11; Issue: 13 Linguagem: Inglês
10.1021/ol901005x
ISSN1523-7060
AutoresJixuan Liang, Jingbo Chen, Fengxiang Du, Xianghui Zeng, Liang Li, Hongbin Zhang,
Tópico(s)Synthesis of β-Lactam Compounds
ResumoNew oxidative dearomatization procedures leading to spiro β-lactams and oxindoles were developed. By a variation of the oxidative reaction conditions, the usefulness of phenolic amides, derived from 4-aminophenol, in the synthesis of structurally different types of molecules was demonstrated.
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