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Facile synthesis of a o-nitrobenzyl photolabile linker for combinatorial chemistry

1996; Elsevier BV; Volume: 37; Issue: 32 Linguagem: Inglês

10.1016/0040-4039(96)01175-6

1873-3581

Simon J. Teague,

Synthetic Organic Chemistry Methods

Two facile syntheses are described of the o-nitrobenzyl alcohol photolabile linker (5). This compound is a valuable intermediate in the preparation of combinatorial libraries, where it allows release from the solid support to give libraries of acids.