Artigo Acesso aberto Revisado por pares

Myocardial Edema: an Overlooked Mechanism of Septic Cardiomyopathy?

2019; Lippincott Williams & Wilkins; Volume: 53; Issue: 5 Linguagem: Inglês

10.1097/shk.0000000000001395

ISSN

1540-0514

Autores

Francisco Vasques‐Nóvoa, Tiago L. Laundos, António J. Madureira, Nuno Bettencourt, José Pedro L. Nunes, Fátima Carneiro, José Artur Paiva, Perpétua Pinto‐do‐Ó, Diana S. Nascimento, Adelino Leite‐Moreira, Roberto Roncon‐Albuquerque,

Tópico(s)

Mechanical Circulatory Support Devices

Resumo

ABSTRACT Septic cardiomyopathy is an increasingly relevant topic in clinical management of septic shock. However, pathophysiological mechanisms and long-term consequences of sepsis-induced myocardial injury are still poorly understood. Herein, new clinical and histological evidence is provided suggesting an association of myocardial edema formation with tissue injury and subsequent remodeling in septic shock patients. This preliminary data supports myocardial edema as a potentially relevant and largely unexplored mechanism of human septic cardiomyopathy.

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