Cystothiazoles C-F, new bithiazole-type antibiotics from the myxobacterium Cystobacter fuscus
1998; Elsevier BV; Volume: 54; Issue: 38 Linguagem: Inglês
10.1016/s0040-4020(98)00694-2
ISSN1464-5416
AutoresYoshihiro Suzuki, Makoto Ojika, Youji Sakagami, Ryosuke Fudou, Shigeru Yamanaka,
Tópico(s)Microbial Natural Products and Biosynthesis
ResumoBithiazole-type antifungal products, cystothiazoles C-F (3–6), have been isolated from a culture broth of the myxobacterium Cystobacter fuscus as minor components. These are structurally related to cystothiazole A (1), which was isolated as a cytotoxic antibiotic from the same microorganism in our previous work. The structures of these compounds were elucidated by spectroscopic analyses. These new compounds inhibit the phytopathogenic fungus, Phytophthora capsici, but are less active than 1.
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