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Difluoroalkylation of Carbonyl Compounds with (1,1-Difluoroalkyl)silane Derivatives

1995; Thieme Medical Publishers (Germany); Volume: 1995; Issue: 07 Linguagem: Inglês

10.1055/s-1995-5070

1437-2096

Toshiki Hagiwara, Takamasa Fuchikami,

Cultural and Social Studies in Latin America

Difluoromethylation and 1,1-difluoroalkylation of carbonyl compounds were achieved by using (difluoromethyl)- or (1,1-difluoroalkyl)silane derivatives in the presence of fluoride or alkoxide ion source.