Artigo Acesso aberto Revisado por pares

Five New Monoterpene Glycosides and Other Compounds from Foeniculi Fructus (Fruit of Foeniculum vulgare MILLER).

1996; Pharmaceutical Society of Japan; Volume: 44; Issue: 2 Linguagem: Inglês

10.1248/cpb.44.337

ISSN

1347-5223

Autores

Masateru Ono, Yasuyuki Ito, Thoru ISHIKAWA, Junichi Kitajima, Yasuko Tanaka, Yujiro Niiho, Toshihiro Nohara,

Tópico(s)

Natural product bioactivities and synthesis

Resumo

Five new monoterpene glycosides, foeniculosides V, VI, VII, VIII and IX, were isolated form Foeniculi Fructus (fruit of Foeniculum vulgare MILLER) along with seven known compounds, zizybeoside I, icaviside A4, syringin, sinapyl alcohol 1, , 3'-di-O-β-D-glucopyranoside, adenosine, threo-anethole glycol and erythro-anethole glycol. The structures of foeniculosides V, VI, VII, VIII and IX were characterized as β-D-glucopyranosides of (1S, 2R, 4S)-2, 4-dihydroxy-1, 8-cineole-2-O-, (1R, 4R, 6R)-4, 6-dihydroxy-1, 8-cineole-6-O-, (1R, 4R, 6R)-4, 6-dihydroxy-1, 8-cineole-4-O-, (1S, 2R, 4R, 6S)-2, 6-dihydroxy-1, 8-cineole-2-O- and (1S, 2R, 4S, 5R)-2, 5-dihydroxy-1, 8-cineole-2-O-, respectively, on the basis of chemical and spectroscopic data.

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