Artigo Acesso aberto Revisado por pares

Asymmetric Michael Reaction Promoted by New Chiral Phase-Transfer Catalysts

2004; Pharmaceutical Society of Japan; Volume: 52; Issue: 5 Linguagem: Inglês

10.1248/cpb.52.646

ISSN

1347-5223

Autores

Shigeru Arai, Kazuyuki Tokumaru, Toyohiko Aoyama,

Tópico(s)

Zeolite Catalysis and Synthesis

Resumo

A catalytic asymmetric Michael reaction promoted by new chiral quaternary ammonium salts is described. The products are obtained with moderate ee (up to 75% ee), and the enantioselectivity is strongly dependent on both the substituents on the aromatic rings and the ammonium moiety in the catalysts.

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