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Unprecedented Reactivity of N-Heterocyclic Carbenes toward DMAD and Aldehydes Leading to Novel Multicomponent Reactions

2003; American Chemical Society; Volume: 5; Issue: 5 Linguagem: Inglês

10.1021/ol0273856

1523-7060

Vijay Nair, S. Bindu, Sreekumar Vellalath, Nigam P. Rath,

Quinazolinone synthesis and applications

A facile synthesis of highly functionalized 2-oxymaleate and furanone derivatives by the multicomponent reaction of 1,3-dimesityl imidazolin-2-ylidene/imidazol-2-ylidene, DMAD, and aldehydes is described.