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A Convenient Synthesis to N -Aryl-Substituted 4-Piperidones

1999; American Chemical Society; Volume: 1; Issue: 8 Linguagem: Inglês

10.1021/ol990930r

1523-7060

David R. Tortolani, Michael A. Poss,

Synthesis of heterocyclic compounds

A general and efficient procedure for the synthesis of N-aryl-substituted 4-piperidones was developed. The general methodology was applied to the synthesis of several different N-aryl-4-piperidones utilizing an expedient two-step process.