Primary Cutaneous Anaplastic Large-Cell Lymphoma
2019; Multidisciplinary Digital Publishing Institute; Volume: 6; Issue: 2 Linguagem: Inglês
10.1159/000500259
ISSN2296-3529
AutoresNerissa Moodley, Patiswa Nombona, Anisa Mosam,
Tópico(s)CNS Lymphoma Diagnosis and Treatment
ResumoA 35-year-old male presented with a 6-month history of asymptomatic, generalised, self-healing lesions. On clinical examination, there were diffuse, ulcerated, necrotic papules and nodules with lymphoedema of the face. Histology sections confirmed atypical lymphoid-type cells which appeared round-to-oval with irregular nuclei (horseshoe-shaped). Immunohistochemistry stains were positive for CD30, CD3, and epithelial membrane antigen. The features were in keeping with an anaplastic large-cell lymphoma, T cell type. This transformed into a systemic variant of the disease after the patient had completed chemotherapy.
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