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Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae

2019; American Society for Microbiology; Volume: 10; Issue: 3 Linguagem: Inglês

10.1128/mbio.01286-19

2161-2129

Geneviève Garriss, Priyanka Nannapaneni, Alexandra S. Simões, Sarah Browall, Karthik Subramanian, Raquel Sá‐Leão, Herman Goossens, Hermı́nia de Lencastre, Birgitta Henriques‐Normark,

Infective Endocarditis Diagnosis and Management

S. pseudopneumoniae is an overlooked pathogen emerging as the causative agent of lower-respiratory-tract infections and associated with chronic obstructive pulmonary disease (COPD) and exacerbation of COPD. However, much remains unknown on its clinical importance and epidemiology, mainly due to the lack of specific markers to distinguish it from S. pneumoniae . Here, we provide a new molecular marker entirely specific for S. pseudopneumoniae and offer a comprehensive view of the virulence and colonization genes found in this species. Finally, our results pave the way for further studies aiming at understanding the pathogenesis and epidemiology of S. pseudopneumoniae .