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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

AUTISM SPECTRUM DISORDER AND POSTNATAL FACTORS: A CASE-CONTROL STUDY IN BRAZIL

2019; Elsevier BV; Volume: 37; Issue: 4 Linguagem: Inglês

10.1590/1984-0462/;2019;37;4;00006

ISSN

1984-0462

Autores

Fernanda Alves Maia, Liliane Marta Mendes de Oliveira, Maria Tereza Carvalho Almeida, Maria Rachel Alves, Vanessa Souza de Araújo Saeger, Victor Bruno da Silva, Victória Spínola Duarte de Oliveira, Hercílio Martelli Júnior, Maria Fernanda Santos Figueiredo Brito, Marise Fagundes Silveira,

Tópico(s)

Child Nutrition and Feeding Issues

Resumo

To estimate the magnitude of the association between Autism Spectrum Disorder (ASD) and postnatal factors in a Brazilian population.A case-control study was performed with 253 individuals diagnosed with ASD and 886 individuals without signs of the disorder. A semi-structured questionnaire and the multiple logistic regression model were adopted in the data analysis. To estimate the magnitude of associations, the crude and adjusted Odds Ratio (OR) was used.An association with the following factors was found: having been born with congenital malformation (OR 4.24; confidence interval of 95% - 95%CI 1.92-9.34), neonatal jaundice (OR 1.43; 95%CI 1.01-2.02), absence of crying at birth and seizure episode in childhood (OR 5.75; 95%CI 3.37-9.81). The magnitude of the association was higher in the children/adolescents who had two or more postnatal complications (OR 6.39; 95%CI 4.10-10.00).The findings of the present study suggest that malformation, neonatal jaundice, absence of crying at birth and seizure episodes in childhood are important factors to be considered when studying the etiology of ASD.

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