Portal de Periódicos da CAPES

Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience

2019; Oxford University Press; Volume: 6; Issue: 8 Linguagem: Inglês

10.1093/ofid/ofz327

2328-8957

Jenna Rossoff, Sonali Chaudhury, Maulin Soneji, Sameer Patel, Soyang Kwon, Amy E. Armstrong, William J. Muller,

Bacterial Identification and Susceptibility Testing

Pediatric patients frequently present with illnesses strongly suggesting infection, but without a clearly identified etiology. Our center has recently added a commercially available plasma metagenomic sequencing assay to its available diagnostic testing. Our experience with the first 100 tests suggests that this technology has good clinical performance with >90% sensitivity.