Produção Nacional
Revisado por pares
Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study
2019; BioMed Central; Volume: 14; Issue: 1 Linguagem: Inglês
10.1186/s13017-019-0253-2
ISSN1749-7922
AutoresMassimo Sartelli, Fikri M. Abu‐Zidan, Francesco M. Labricciosa, Yoram Kluger, Federico Coccolini, Luca Ansaloni, Ari Leppäniemi, Andrew W. Kirkpatrick, Matti Tolonen, Cristian Tranà, Jean‐Marc Regimbeau, Timothy Craig Hardcastle, Renol Koshy, Ashraf Abbas, Ulaş Aday, A. R. K. Adesunkanmi, A Ajibade, Lali Akhmeteli, Emrah Akın, Nezih Akkapulu, Alhenouf Alotaibi, Fatih Altıntoprak, Dimitrios Anyfantakis, Boyko Atanasov, Goran Augustin, Constança Azevedo, Miklosh Bala, Dimitrios Balalis, Oussama Baraket, Suman Baral, Or Barkai, Marcelo A. Beltrán, Roberto Bini, Konstantinos Bouliaris, Ana B. Caballero, Valentin Calu, Marco Catani, Marco Ceresoli, Vasileios Charalampakis, Asri Che Jusoh, Massimo Chiarugi, Nicola Cillara, Raquel Cobos Cuesta, Luigi Cobuccio, Gianfranco Cocorullo, Elif Çolak, Luigi Conti, Yunfeng Cui, Belinda De Simone, Samir Delibegović, Zaza Demetrashvili, Δημήτριος Δημητριάδης, Ana Dimova, Agron Dogjani, Mushira Enani, Federica Farina, Francesco Ferrara, Domitilla Foghetti, Tommaso Fontana, Gustavo Pereira Fraga, Mahir Gachabayov, Gérard Grelpois, Wagih Ghnnam, Teresa Giménez Maurel, Georgios Gkiokas, Carlos Augusto Gomes, Ali Güner, Sanjay Gupta, Andreas Hecker, Élcio Hirano, Adrien Montcho Hodonou, M Hut'an, Igor Ilaschuk, Orestis Ioannidis, Arda Işık, Г Б Ивахов, Sumita Jain, Mantas Jokubauskas, Aleksandar Karamarković, Robin Kaushik, Jakub Kenig, Vladimir Khokha, Denis Khokha, Jae Il Kim, Victor Kong, Dimitris P. Korkolis, Vitor Favali Kruger, Ashok Kshirsagar, Romeo Lages Simões, Andrea Lanaia, Konstantinos Lasithiotakis, Pedro Leão, Miguel León Arellano, Holger Listle, Andrey Litvin, Aintzane Lizarazu, Eudaldo López-Tomassetti Fernández, Eftychios Lostoridis, Davide Luppi, Gustavo M. Machaín, Piotr Major, Dimitrios K. Manatakis, Marianne Marchini Reitz, Athanasios Marinis, Daniele Marrelli, Aleix Martínez‐Pérez, Sanjay Marwah, Michael McFarlane, Mirza Mesic, Cristian Meşină, Nikolaos Michalopoulos, Evangelos Misiakos, Felipe Gonçalves Moreira, Ouadii Mouaqit, Ali Muhtaroğlu, Noel Naidoo, Ionuţ Negoi, Zane Nikitina, Ioannis Nikolopoulos, G. Nita, Savino Occhionorelli, Iyiade Olatunde Olaoye, Carlos A. Ordóñez, Zeynep Özkan, Ajay Kumar Pal, Gian Marco Palini, Kyriaki Papageorgiou, Dimitris Papagoras, Francesco Pata, Michał Pędziwiatr, Jorge Pereira, Gerson Alves Pereira Júnior, Gennaro Perrone, Tadeja Pintar, Magdalena Pisarska, O. M. Plehutsa, Mauro Podda, Gaetano Poillucci, Martha Quiodettis, Tuba Rahim, Daniel Ríos‐Cruz, Gabriel Rodrigues, Dmytry Rozov, Boris Sakakushev, Ibrahima Sall, А. В. Сажин, J. Semião, Taanya Sharda, Vishal G. Shelat, Giovanni Sinibaldi, Dmitrijs Skicko, M Škrovina, Dimitrios Stamatiou, Marco Stella, Marcin Strzałka, Ruslan Sydorchuk, Ricardo Alessandro Teixeira Gonsaga, Joël Noutakdie Tochie, Gia Tomadze, Lara Ugoletti, Jan Ulrych, Toomas Ümarik, Mustafa Yener Uzunoğlu, A Vasilescu, Osborne Vaz, András Vereczkei, N Vlad, Maciej Wałędziak, Ali Yahya, Ömer Yalkın, Tonguç Utku Yılmaz, Ali Ekrem Ünal, Yuan Kuo-Ching, Sanoop Koshy Zachariah, Justas Žilinskas, Maurizio Zizzo, Vittoria Pattonieri, Gian Luca Baiocchi, Fausto Catena,
Tópico(s)Appendicitis Diagnosis and Management
ResumoTiming and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peritonitis and to develop a warning score system, based on easily recognizable and assessable variables, globally accepted.This worldwide multicentre observational study included 153 surgical departments across 56 countries over a 4-month study period between February 1, 2018, and May 31, 2018.A total of 3137 patients were included, with 1815 (57.9%) men and 1322 (42.1%) women, with a median age of 47 years (interquartile range [IQR] 28-66). The overall in-hospital mortality rate was 8.9%, with a median length of stay of 6 days (IQR 4-10). Using multivariable logistic regression, independent variables associated with in-hospital mortality were identified: age > 80 years, malignancy, severe cardiovascular disease, severe chronic kidney disease, respiratory rate ≥ 22 breaths/min, systolic blood pressure < 100 mmHg, AVPU responsiveness scale (voice and unresponsive), blood oxygen saturation level (SpO2) < 90% in air, platelet count < 50,000 cells/mm3, and lactate > 4 mmol/l. These variables were used to create the PIPAS Severity Score, a bedside early warning score for patients with acute peritonitis. The overall mortality was 2.9% for patients who had scores of 0-1, 22.7% for those who had scores of 2-3, 46.8% for those who had scores of 4-5, and 86.7% for those who have scores of 7-8.The simple PIPAS Severity Score can be used on a global level and can help clinicians to identify patients at high risk for treatment failure and mortality.
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