Portal de Periódicos da CAPES

Electrochemical detection mechanism of dopamine and uric acid on titanium nitride-reduced graphene oxide composite with and without ascorbic acid

2019; Elsevier BV; Volume: 298; Linguagem: Inglês

10.1016/j.snb.2019.126872

1873-3077

Jiao Feng, Qun Li, Jianpeng Cai, Tao Yang, Junhong Chen, Xinmei Hou,

Electrochemical Analysis and Applications

Chrysanthemum-like titanium nitride-reduced graphene oxide (TiN-rGO) composite was synthesized involving the hydrothermal and nitridation process. The rGO does not change the chrysanthemum-like structure of TiN while enhancing the electroactive surface area. Based on this, the electrochemical sensor was prepared by adopting TiN-rGO to modify glassy carbon electrode (GCE). Due to the synergic effects of TiN and rGO, the sensor exhibits good electrocatalytic activity especially toward the detection of dopamine (DA) and uric acid (UA). The linear detection ranges are 5–175 μM and 30–215 μM, with detection limits of 0.159 μM and 0.350 μM for DA and UA (S/N = 3), respectively. When ascorbic acid (AA) coexists with DA and UA, the peaks of the three substances based on the electrode can be separated. The electrochemical detection mechanism shows that AA can be detected at low concentrations, i.e. below 100 μM, which can meet the needs of human body. In addition, the sensor exhibits good anti-interference, stability, reproducibility and satisfactory recovery results in real samples.