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A New Brief Clinical Assessment of Lower Urinary Tract Symptoms for Women and Men: LURN SI-10

2019; Lippincott Williams & Wilkins; Volume: 203; Issue: 1 Linguagem: Inglês

10.1097/ju.0000000000000465

1527-3792

David Cella, Abigail R. Smith, James W. Griffith, Ziya Kırkalı, Kathryn E. Flynn, Catherine S. Bradley, J. Eric Jelovsek, Brenda W. Gillespie, Brian T. Helfand, Pooja Talaty, Kevin P. Weinfurt,

Urinary Tract Infections Management

No AccessJournal of UrologyAdult Urology1 Jan 2020A New Brief Clinical Assessment of Lower Urinary Tract Symptoms for Women and Men: LURN SI-10 David Cella, Abigail R. Smith, James W. Griffith, Ziya Kirkali, Kathryn E. Flynn, Catherine S. Bradley, J. Eric Jelovsek, Brenda W. Gillespie, Brian T. Helfand, Pooja Talaty, and Kevin P. Weinfurt David CellaDavid Cella *Correspondence: Northwestern University, 633 North St. Clair, 19th Floor, Chicago, Illinois 60611 telephone: 312-503-1086; E-mail Address: [email protected] Northwestern University Feinberg School of Medicine, Chicago, Illinois More articles by this author , Abigail R. SmithAbigail R. Smith Arbor Research Collaborative for Health, Ann Arbor, Michigan More articles by this author , James W. GriffithJames W. Griffith Northwestern University Feinberg School of Medicine, Chicago, Illinois More articles by this author , Ziya KirkaliZiya Kirkali National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland More articles by this author , Kathryn E. FlynnKathryn E. Flynn Medical College of Wisconsin, Milwaukee, Wisconsin More articles by this author , Catherine S. BradleyCatherine S. Bradley University of Iowa Carver College of Medicine, Iowa City, Iowa More articles by this author , J. Eric JelovsekJ. Eric Jelovsek Duke University Medical Center, Durham, North Carolina More articles by this author , Brenda W. GillespieBrenda W. Gillespie University of Michigan, Ann Arbor, Michigan More articles by this author , Brian T. HelfandBrian T. Helfand NorthShore University Health System, Glenview, Illinois More articles by this author , Pooja TalatyPooja Talaty NorthShore University Health System, Glenview, Illinois More articles by this author , and Kevin P. WeinfurtKevin P. Weinfurt Duke University Medical Center, Durham, North Carolina More articles by this author and the LURN Study Group View All Author Informationhttps://doi.org/10.1097/JU.0000000000000465AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Lower urinary tract symptoms are common in men and women. Members of the LURN (Lower Urinary Tract Dysfunction Research Network) sought to create a brief, clinically relevant tool to improve existing measurements of lower urinary tract symptoms in men and women. Materials and Methods: Using a modified Delphi methodology during an expert consensus meeting we reduced the LURN CASUS (Comprehensive Assessment of Self-Reported Urinary Symptoms) questionnaire to a brief set of clinically relevant items measuring lower urinary tract symptoms. The sum score of these items was evaluated by comparing it to the AUA SI (American Urological Association Symptom Index), the UDI-6 (Urinary Distress Inventory Short Form) in women only and the CASUS lower urinary tract symptoms screening questions using the Pearson correlation, regression analysis and ROC curves. Results: The LURN SI-10 (10-Item LURN Symptom Index) assesses urinary frequency, nocturia, urgency, incontinence, bladder pain, voiding and post-micturition symptoms (score range 0 to 38). The correlation between LURN SI-10 and AUA SI scores was 0.77 in men and 0.70 in women. The UDI-6 and the LURN SI-10 correlated highly in women (r=0.76). The LURN SI-10 showed good accuracy to predict moderate and severe lower urinary tract symptoms as defined by the AUA SI (ROC AUC range 0.82-0.90). Similar accuracy was shown in predicting different levels of symptom status using the UDI-6 (AUC range 0.84-0.86). Conclusions: The LURN SI-10 correlates well with the AUA SI and the UDI-6. It includes items related to a broader spectrum of lower urinary tract symptoms, particularly incontinence, bladder pain and post-micturition symptoms, and it applies to men and women. References 1. : The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) study. BJU Int 2009; 104: 352. Google Scholar 2. : The overlap of storage, voiding and postmicturition symptoms and implications for treatment seeking in the USA, UK and Sweden: EpiLUTS. BJU Int, suppl., 2009; 103: 12. Google Scholar 3. : Self-report measurement of lower urinary tract symptoms: a commentary on the literature since 2011. Curr Urol Rep 2012; 13: 420. Google Scholar 4. . The International Consultation on Incontinence Modular Questionnaire:www.iciq.net. J Urol 2006; 175: 1063. Link, Google Scholar 5. : The American Urological Association Symptom Index for benign prostatic hyperplasia. 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J Urol 2018; 199: 1023. Link, Google Scholar 11. : Health-related quality of life measures for women with urinary incontinence: the incontinence impact questionnaire and the urogenital distress inventory. Qual Life Res 1994; 3: 291. Google Scholar The corresponding author certifies that, when applicable, a statement(s) has been included in the manuscript documenting institutional review board, ethics committee or ethical review board study approval; principles of Helsinki Declaration were followed in lieu of formal ethics committee approval; institutional animal care and use committee approval; all human subjects provided written informed consent with guarantees of confidentiality; IRB approved protocol number; animal approved project number. This is publication No. 22 of the LURN. Supported by NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) through cooperative agreements (Grants DK097780, DK097772, DK097779, DK099932, DK100011, DK100017, DK097776 and DK099879), at Northwestern University in part by NIH (National Institutes of Health) NCATS (National Center for Advancing Translational Sciences) Grant No. UL1TR001422 and by NIDDK Grant K23-DK110417 (N. Siddiqui). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH (National Institutes of Health). No direct or indirect commercial, personal, academic, political, religious or ethical incentive is associated with publishing this article. © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byHarper J, Desai A, Maalouf N, Yang H, Antonelli J, Tasian G, Lai H, Reese P, Curatolo M, Kirkali Z, Al-Khalidi H, Wessells H, Scales C, Reese P, Tasian G, Ziemba J, Funsten E, Mussell A, McCune R, Shah S, Jain A, Selman-Fermin A, Maalouf N, Antonelli J, Johnson B, Pearle M, Baker L, Piskator B, Obiaro J, Rangel C, Hill M, Harper J, Wessells H, Curatolo M, Edwards T, Sorensen M, Sweet R, Baxter T, Covert H, Ayala E, Flint L, Cho G, Marshall G, Desai A, Lai H, Du K, Mueller S, Black L, Klim A, Scales C, Al-Khalidi H, Corneli A, Reeve B, Weinfurt K, Yang H, Andersen D, Johnson L, Dodd A, Thompson O, Dombeck C, McKenna K, Swezey T, Kirkali Z and Mullins C (2023) Risk Factors for Increased Stent-associated Symptoms Following Ureteroscopy for Urinary Stones: Results From STENTSJournal of Urology, Sebesta E, Gleicher S, Kaufman M, Dmochowski R and Reynolds W (2022) Associations Between Unmet Social Needs and Overactive BladderJournal of Urology, VOL. 208, NO. 5, (1106-1115), Online publication date: 1-Nov-2022.Glaser A, Mansfield S, Smith A, Helfand B, Lai H, Sarma A, Yang C, Taddeo M, Clemens J, Cameron A, Flynn K, Andreev V, Fraser M, Erickson B, Kirkali Z and Griffith J (2022) Impact of Sleep Disturbance, Physical Function, Depression and Anxiety on Male Lower Urinary Tract Symptoms: Results from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)Journal of Urology, VOL. 208, NO. 1, (155-163), Online publication date: 1-Jul-2022. Volume 203Issue 1January 2020Page: 164-170Supplementary Materials Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.Keywordsfemalemalelower urinary tract symptomsurinary bladderpatient reported outcome measuresAcknowledgmentThe following individuals were instrumental in planning and performing this study at participating institutions: Principal Investigators Drs. Cindy Amundsen and Kevin Weinfurt, Co-Investigators Drs. Kathryn Flynn, Matthew O. Fraser, Todd Harshbarger, Eric Jelovsek, Aaron Lentz, Drew Peterson, Nazema Siddiqui and Alison Weidner, and Study Coordinators Carrie Dombeck, Robin Gilliam, Akira Hayes and Shantae McLean, Duke University, Durham, North Carolina (DK097780); Principal Investigators Drs. Karl Kreder and Catherine S. Bradley, Co-Investigators Drs. Bradley A. Erickson, Susan K. Lutgendorf, Vince Magnotta, Michael A. O’Donnell and Vivian Sung, and Study Coordinator Ahmad Alzubaidi, University of Iowa, Iowa City, Iowa (DK097772); Principal Investigator Dr. David Cella, Co-Investigators Drs. James W. Griffith, Kimberly Kenton, Christina Lewicky-Gaupp, Todd Parrish, Jennie Yufen Chen and Margaret Mueller, Study Coordinators Sarah Buono, Maria Corona, Beatriz Menendez, Alexis Siurek, Meera Tavathia, Veronica Venezuela and Azra Muftic, Northwestern University, and Principal Investigator Dr. Brian T. Helfand, and Pooja Talaty and Jasmine Nero, NorthShore University HealthSystem, Chicago, Illinois (DK097779); Principal Investigator Dr. J. Quentin Clemens, Co-Investigators Drs. Mitch Berger, John DeLancey, Dee Fenner, Rick Harris, Steve Harte, Anne P. Cameron and John Wei, and Study Coordinators Morgen Barroso, Linda Drnek, Greg Mowatt and Julie Tumbarello, University of Michigan Health System (DK099932) and Principal Investigator Dr. Robert Merion, Co-Investigators Drs. Victor Andreev, Brenda Gillespie, Gang Liu and Abigail Smith, Project Manager Melissa Fava, Clinical Study Process Manager Peg Hill-Callahan, Clinical Monitor Timothy Buck, Research Analysts Margaret Helmuth and Jon Wiseman, and Project Associate Julieanne Lock, Data Coordinating Center, Arbor Research Collaborative for Health (DK097776 and DK099879), Ann Arbor, Michigan; Principal Investigator Dr. Claire Yang, Co-Investigator Dr. John L. Gore, and Study Coordinators Alice Liu and Brenda Vicars, University of Washington, Seattle, Washington (DK100011); Principal Investigators Drs. Gerald L. Andriole and H. Henry Lai, Co-Investigator Dr. Joshua Shimony and Study Coordinators Susan Mueller, Heather Wilson, Deborah Ksiazek and Aleksandra Klim, Washington University in St. Louis, St. Louis, Missouri (DK100017); and Project Scientist Dr. Ziya Kirkali, Project Officer Dr. Christopher Mullins, and NIH (National Institutes of Health) Personnel Drs. Tamara Bavendam and Robert Star, and Jenna Norton, Division of Kidney, Urology and Hematology, NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases), Bethesda, Maryland.MetricsAuthor Information David Cella Northwestern University Feinberg School of Medicine, Chicago, Illinois *Correspondence: Northwestern University, 633 North St. Clair, 19th Floor, Chicago, Illinois 60611 telephone: 312-503-1086; E-mail Address: [email protected] More articles by this author Abigail R. Smith Arbor Research Collaborative for Health, Ann Arbor, Michigan More articles by this author James W. Griffith Northwestern University Feinberg School of Medicine, Chicago, Illinois More articles by this author Ziya Kirkali National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland More articles by this author Kathryn E. Flynn Medical College of Wisconsin, Milwaukee, Wisconsin More articles by this author Catherine S. Bradley University of Iowa Carver College of Medicine, Iowa City, Iowa More articles by this author J. Eric Jelovsek Duke University Medical Center, Durham, North Carolina More articles by this author Brenda W. Gillespie University of Michigan, Ann Arbor, Michigan More articles by this author Brian T. Helfand NorthShore University Health System, Glenview, Illinois More articles by this author Pooja Talaty NorthShore University Health System, Glenview, Illinois More articles by this author Kevin P. Weinfurt Duke University Medical Center, Durham, North Carolina More articles by this author Expand All The corresponding author certifies that, when applicable, a statement(s) has been included in the manuscript documenting institutional review board, ethics committee or ethical review board study approval; principles of Helsinki Declaration were followed in lieu of formal ethics committee approval; institutional animal care and use committee approval; all human subjects provided written informed consent with guarantees of confidentiality; IRB approved protocol number; animal approved project number. This is publication No. 22 of the LURN. Supported by NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) through cooperative agreements (Grants DK097780, DK097772, DK097779, DK099932, DK100011, DK100017, DK097776 and DK099879), at Northwestern University in part by NIH (National Institutes of Health) NCATS (National Center for Advancing Translational Sciences) Grant No. UL1TR001422 and by NIDDK Grant K23-DK110417 (N. Siddiqui). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH (National Institutes of Health). No direct or indirect commercial, personal, academic, political, religious or ethical incentive is associated with publishing this article. Advertisement PDF downloadLoading ...