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Role of 18F-flurodeoxyglucose in orthopaedic implant-related infection

2019; Lippincott Williams & Wilkins; Volume: 40; Issue: 9 Linguagem: Inglês

10.1097/mnm.0000000000001063

1473-5628

Amit Bhoil, Hendrick Caw, Sobhan Vinjamuri,

Hematological disorders and diagnostics

Infection and inflammation are a common occurrence with orthopaedic procedures. Anatomical modalities can show the transformation in the disease process; however, these may occur later when compared with functional imaging modalities that are more likely to identify early disease patterns. Various molecular imaging modalities such as three-phase bone scintigraphy, labelled leucocyte scintigraphy, as well as radiolabelled antibiotics and immunoglobulins have been considered and have played key roles in assisting clinical decision-making. While 18F-flurodeoxyglucose (FDG) PET/computed tomography (CT) has been relatively well established in cancer pathways, it has the potential to contribute to surgical decision making for possible osteomyelitis post-metal implant surgery. In this article, we present a review of recently used tracers, and share our experience with using 18F-FDG PET/CT studies in a few diverse clinical settings related to post-metal implant osteomyelitis.