Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs
2019; Elsevier BV; Volume: 134; Issue: 13 Linguagem: Inglês
10.1182/blood.2019001289
ISSN1528-0020
AutoresSorcha O’Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Catherine Garnett, Laura Godfrey, Nicholas T. Crump, Gary Wright, Sarah Inglott, Hua Peng, Bethan Psaila, Benjamin Povinelli, David J. H. F. Knapp, Antonio Agraz-Doblás, Clara Bueno, Ignacio Varela, Phillip R. Bennett, Hashem Koohy, Suzanne M. Watt, Anastasios Karadimitris, Adam J. Mead, Phillip Ancliff, Paresh Vyas, Pablo Menéndez, Thomas A. Milne, Irene Roberts, Anindita Roy,
Tópico(s)T-cell and B-cell Immunology
ResumoAbstract By comparing fetal and adult B-lymphopoiesis, the authors identify a prepro–B-cell subset in humans that marks the origin of B-cell lineage commitment in utero.
Referência(s)