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KEGG Mapper for inferring cellular functions from protein sequences

2019; Wiley; Volume: 29; Issue: 1 Linguagem: Inglês

10.1002/pro.3711

1469-896X

Minoru Kanehisa, Yoko Sato,

Glycosylation and Glycoproteins Research

Abstract KEGG is a reference knowledge base for biological interpretation of large‐scale molecular datasets, such as genome and metagenome sequences. It accumulates experimental knowledge about high‐level functions of the cell and the organism represented in terms of KEGG molecular networks, including KEGG pathway maps, BRITE hierarchies, and KEGG modules. By the process called KEGG mapping, a set of protein coding genes in the genome, for example, can be converted to KEGG molecular networks enabling interpretation of cellular functions and other high‐level features. Here we report a new version of KEGG Mapper, a suite of KEGG mapping tools available at the KEGG website ( https://www.kegg.jp/ or https://www.genome.jp/kegg/ ), together with the KOALA family tools for automatic assignment of KO (KEGG Orthology) identifiers used in the mapping.