Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents
2019; Multidisciplinary Digital Publishing Institute; Volume: 24; Issue: 17 Linguagem: Inglês
10.3390/molecules24173077
ISSN1433-1373
AutoresAlcives Avila‐Sorrosa, Jazz D. Tapia-Alvarado, Benjamín Nogueda‐Torres, Karla Fabiola Chacón-Vargas, Francisco Díaz-Cedillo, Marı́a Elena Vargas-Dı́az, David Morales‐Morales,
Tópico(s)Synthesis and Biological Evaluation
ResumoA series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.
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