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Clinical Impact of a Comprehensive Medication Management Service in Primary Health Care

2019; SAGE Publishing; Volume: 34; Issue: 2 Linguagem: Inglês

10.1177/0897190019866309

1531-1937

Bruna Damázio Santos, Mariana Martins Gonzaga do Nascimento, Grazielli Cristina Batista de Oliveira, Yone de Almeida Nascimento, Juliana Vaz de Melo Mambrini, Annaline Stiegert Cid, Taíza Graziele Costa Piovesan, Laura Barbosa Fernandes, Úrsula Martins, Carina de Morais Neves, Danielle Fernandes da Silva, Djenane Ramalho de Oliveira,

Medication Adherence and Compliance

To evaluate the clinical impact of a comprehensive medication management (CMM) service in a Brazilian primary health-care setting.A quasi-experimental study has been carried out between July 2014 and November 2016 with patients who received the service in the primary care setting of a Brazilian city (n = 1057). Factors associated with drug therapy problems (DTP) detection in the initial assessment were evaluated by performing univariate and multivariate analyzes. To evaluate the impact of the CMM service, a linear regression model was constructed from the difference between the initial and final values of the clinical and laboratory parameters adjusted by multiple variables.A total of 1642 DTPs was identified, the most prevalent one being "nonadherence" (31.9%) and the "need for additional drug therapy" (22.9%). The use of 5 or more medications and the presence of 3 or more diseases were positively associated with the identification of 3 or more DTPs during the initial assessment. Even after multiple adjustments, a statistically significant reduction has been observed in the values of glycated hemoglobin, systolic blood pressure, low-density cholesterol, and total cholesterol.The CMM service contributed to the resolution of DTP and showed positive clinical impact in primary health care in the studied setting.