Portal de Periódicos da CAPES

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle

2019; American Association for the Advancement of Science; Volume: 365; Issue: 6455 Linguagem: Inglês

10.1126/science.aaw2619

1095-9203

Virginia M. Howick, Andrew J. C. Russell, Tallulah Andrews, Haynes Heaton, Adam J. Reid, Kedar Nath Natarajan, Hellen Butungi, Tom Metcalf, Lisa Verzier, Julian C. Rayner, Matthew Berriman, Jeremy K. Herren, Oliver Billker, Martin Hemberg, Arthur M. Talman, Mara Lawniczak,

Invertebrate Immune Response Mechanisms

Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We profiled the single-cell transcriptomes of thousands of individual parasites, deriving the first high-resolution transcriptional atlas of the entire