Voltar
Artigo Acesso aberto Produção Nacional
BIBTEX RIS

Low levels of HDL-cholesterol and peripheral artery disease: Protocol for systematic review and meta-analysis

2019; Volume: 4; Issue: 1 Linguagem: Inglês

10.15761/cdm.1000195

ISSN

2398-8878

Autores

Leonardo Roever, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha‐Silva, João Lucas O’Connell, Fernanda Rodrigues de Souza, Poliana Rodrigues Alves Duarte, Hugo Ribeiro Zanetti, Anaisa Silva Roerver-Borges, Fernando César Veloso, Thiago Montes Fidale, Antonio Casella–Filho, Paulo Magno Martins Dourado, Antônio Carlos Palandri Chagas, Sadeq Ali‐Hasan‐Al‐Saegh, Paulo Eduardo Ocke Reis, Rogério de Melo Costa Pinto, Gustavo B.F. Oliveira, Álvaro Avezum, Mansueto Neto, André Rodrigues Durães, Rose Mary Ferreira Lisboa da Silva, Antônio José Grande, Celise Denardi, Renato D. Lópes, Nitesh Nerlekar, Shahab Alizadeh, Adrían V. Hernández, Maria Inês da Rosa, Gary Tse, Tong Liu, Giuseppe Biondi‐Zoccai,

Tópico(s)

Antiplatelet Therapy and Cardiovascular Diseases

Resumo

Purpose of review: HDL-C is believed to retard the formation of atherosclerotic lesions by removing excess cholesterol from cells and preventing endothelial dysfunction.However, there are no systematic analyses or well-conducted meta-analyses to evaluate the relationship between very low HDL-Cand stroke.Patients with peripheral artery disease (PAD) have been found to suffer from diabetes, obesity, lipid abnormalities, including elevated levels of total and LDL-cholesterol as well as triglyceride levels.The aim of this study is to examine this association of very low HDL-Cwith stroke in different ages and sex. Recent findings:The update systematic review and meta-analysis will be conducted using published studies that will be identified from electronic databases (ie, PubMed, EMBASE, Web of Science, and Google Scholar.Studies that (1) examined the association between very low HDL-Cand stroke, (2) had a longitudinal or prospective cohort design, (3) will conducted among in adults aged 34 to 70 years.,(4) provided sufficient data for calculating odds ratios (ORs) or relative risk with a 95% CI, (5) were published as original articles written in English or other languages, and (6) have been published until January 2019 will be included.Study selection, data collection, quality assessment and statistical syntheses will be conducted based on discussions among investigators.

Referência(s)