Gene Therapy: Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework‐8 (ZIF‐8) (Small 36/2019)
2019; Wiley; Volume: 15; Issue: 36 Linguagem: Inglês
10.1002/smll.201970193
ISSN1613-6829
AutoresArpita Poddar, José Javier Conesa, Kang Liang, Sudip Dhakal, Philipp Reineck, Gary Bryant, Eva Pereiro, Raffaele Riccò, Heinz Amenitsch, Christian J. Doonan, Xavier Mulet, Cara M. Doherty, Paolo Falcaro, Ravi Shukla,
Tópico(s)Metal-Organic Frameworks: Synthesis and Applications
ResumoGene therapy utilizing non-viral delivery systems still lags behind its viral counterpart despite being the safer method. In article number 1902268, Ravi Shukla and co-workers explore the potential of metal–organic frameworks (MOFs) for gene delivery. The most fundamental aspect of DNA, its ability to translate into proteins, is investigated to determine the suitability of MOFs as delivery agents for gene therapy. The cover illustrates DNA embedded in the meshwork of ZIF-8. Kate Rowe is acknowledged for framework photograph.
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