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BIBTEX RIS

CUTANEOUS LUPUS MIMICKING SECONDARY SYPHILIS IN A PATIENT WITH POSITIVE ANTICARDIOLIPIN ANTIBODY - A CASE REPORT

2019; Linguagem: Inglês

10.5151/sbr2019-069

2357-7282

CAUÊ JOSÉ PEDROSO PINHEIRO DA SILVA, Julia Deitos, Andressa Caroline Kuzma, LUISA MANFREDIN VILA, JACKSON DANRLEI BALBINOT, Lucas Thiesen Pientka, Ana Paula Adame, Márcio Augusto Nogueira,

Syphilis Diagnosis and Treatment

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, which etiology is not yet well understood. SLE manifests itself in various systems, such as the skin, joints, central nervous system and kidneys. Syphilis is a disease caused by Treponema pallidum infection, and it is mostly transmitted via direct contact with a syphilitic sore on the skin or mucous membranes. Both diseases, albeit different in their etiopathogenesis, can affect many systems and have similar clinical manifestations. The dermatologic findings of secondary syphilis are variable, and may mimic cutaneous lupus, which can be differentiated by biopsy of the lesion. The symptoms of malar rash and photosensitivity occur in 30-40% of SLE patients, while dermatological manifestations occur in 88-100% of cases of secondary syphilis. Non-treponemal tests to diagnosis syphilis have a high number of false-positive results, specially in patients with SLE, antiphospholipid syndrome or other diseases of the connective tissue.