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OC17.02: Assessment of fetal right ventricular systolic function: nomograms of fractional area change by 2D‐echocardiography

2019; Wiley; Volume: 54; Issue: S1 Linguagem: Inglês

10.1002/uog.20535

1469-0705

O. Gómez, L. Guirado, I. Soveral, Brenda Valenzuela‐Alcaráz, M. Rodríguez‐López, Laura García‐Otero, X. Torres, Á. Sepúlveda‐Martínez, M. Escobar, J. Martı́nez, Mark K. Friedberg, E. Gratacós, F. Crispi,

Pregnancy and preeclampsia studies

Right ventricular (RV) fractional area change (FAC) is a 2D-echocardiographic parameter to assess RV global systolic function. Fetal reference ranges are not yet available. Our aims were: to study prenatal RV FAC feasibility and reproducibility and to construct nomograms for RV FAC and end-diastolic and end-systolic RV areas throughout gestation. Prospective cohort study including 602 low-risk singleton pregnancies undergoing a fetal echocardiography from 18-41 weeks of gestation. RV end-diastolic and end-systolic areas were measured following standard recommendations for ventricular dimensions and strict landmarks to identify the phases of the cardiac cycle. RV FAC was calculated as: [(ED area – ES area) / ED area] x 100. RV FAC intra- and inter-observer reproducibility was evaluated in 45 fetuses by calculating the interclass correlation coefficient (ICC). Parametric regressions were tested to model each parameter against gestational age (GA) and estimated fetal weight (EFW). RV areas and FAC were successfully obtained in ∼99% of fetuses with acceptable reproducibility [FAC ICC (95% confidence interval): 0.69 (0.44-0.83)]. Nomograms were constructed for RV end-diastolic and end-systolic areas and FAC. RV areas showed a quadratic and logarithmic increase with GA and EFW, respectively. In contrast, RV FAC showed a slight quadratic decrease throughout gestation (figure 1). The best models for RV areas and FAC were a second degree polynomial. Supporting information can be found in the online version of this abstract Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.