Artigo Acesso aberto Revisado por pares

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells

2019; American Association for the Advancement of Science; Volume: 5; Issue: 10 Linguagem: Inglês

10.1126/sciadv.aay3068

ISSN

2375-2548

Autores

Gary LeRoy, Ozgur Oksuz, Nicolas Descostes, Yuki Aoi, Rais A. Ganai, Havva Ortabozkoyun, Jia-Ray Yu, Chul‐Hwan Lee, James M. Stafford, Ali Shilatifard, Danny Reinberg,

Tópico(s)

Epigenetics and DNA Methylation

Resumo

Chromatin-bound LEDGF and HDGF2 proteins allow RNAPII to overcome the nucleosome-induced block to transcription.

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