Artigo Acesso aberto Produção Nacional Revisado por pares

High level of exposure to hepatitis B virus infection in a vulnerable population of a low endemic area: A challenge for vaccination coverage

2019; Elsevier BV; Volume: 90; Linguagem: Inglês

10.1016/j.ijid.2019.09.029

ISSN

1878-3511

Autores

Sabrina Moreira dos Santos Weis-Torres, Sonia Maria Fernandes Fitts, Wesley Márcio Cardoso, Minoru German Higa Júnior, Lívia Alves Lima, Larissa Melo Bandeira, Vivianne Oliveira Landgraf Castro, Fátima Aparecida Carneiro, Luciana María Marangoni Iglecias, Gabriela Alves Cesar, Tayana Serpa Ortiz Tanaka, Marco Antonio Moreira Puga, Grazielli Rocha de Rezende, Júlio Croda, Bárbara V. Lago, Ana Rita Coimbra Motta-Castro,

Tópico(s)

Hepatitis Viruses Studies and Epidemiology

Resumo

ObjectivesTo evaluate the epidemiological and molecular features of HBV infection among recyclable waste collectors.MethodsThe participants were recruited from the dumping ground and recycling cooperatives in Campo Grande, Brazil, and were screened for hepatitis B and C, and HIV serological markers by ELISA, confirmed by PCR.ResultsAmong 278 participants, 63.7% (95% CI: 58.0–69.3) were considered susceptible to HBV infection. The prevalence rate of HBV exposure was 10.1% (95% CI: 6.5–13.6) and 0.4% (95% CI: 0.1–0.6) were chronic carriers. Age ≥45 years (AOR = 7.15), history of homosexual contact (AOR = 5.29), tattoo (AOR = 4.92) and history of surgery (AOR = 2.89) were factors associated with ever infection. Age 18–25 years (AOR = 4.63), educational level ≥9 years (AOR = 1.98) and knowledge about HBV transmission (AOR = 3.08) were associated with serological HBV vaccination like profile (26.2%; 95% CI: 21.1–31.4).ConclusionsDespite the availability and efficacy of HBV vaccine, this study found high HBV exposure and proportion of susceptible adults in a low endemic area. Vaccination and screening campaigns using accessible language to the economically disadvantaged populations can reduce the number of people susceptible to HBV infection.

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