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ASSESSMENT OF SURGICAL MARGINS IN RENAL CELL CARCINOMA AFTER NEPHRON SPARING: A COMPARATIVE STUDY

2005; Lippincott Williams & Wilkins; Volume: 173; Issue: 4 Linguagem: Inglês

10.1097/01.ju.0000148360.47191.5e

1527-3792

F. Porpiglia, Cristian Fiori, Carlo Terrone, Enrico Bollito, Dario Fontana, Roberto Mario Scarpa,

Bladder and Urothelial Cancer Treatments

No AccessJournal of UrologyAdult Urology: Oncology: Renal/Upper Tract/Bladder1 Apr 2005ASSESSMENT OF SURGICAL MARGINS IN RENAL CELL CARCINOMA AFTER NEPHRON SPARING: A COMPARATIVE STUDYLAPAROSCOPY VS OPEN SURGERY FRANCESCO PORPIGLIA, CRISTIAN FIORI, CARLO TERRONE, ENRICO BOLLITO, DARIO FONTANA, and ROBERTO MARIO SCARPA FRANCESCO PORPIGLIAFRANCESCO PORPIGLIA More articles by this author , CRISTIAN FIORICRISTIAN FIORI More articles by this author , CARLO TERRONECARLO TERRONE More articles by this author , ENRICO BOLLITOENRICO BOLLITO More articles by this author , DARIO FONTANADARIO FONTANA More articles by this author , and ROBERTO MARIO SCARPAROBERTO MARIO SCARPA More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000148360.47191.5eAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compared the status of the peritumoral parenchyma after open and laparoscopic nephron sparing surgery for renal cell carcinoma. Materials and Methods: The records of 64 consecutive patients who underwent nephron sparing surgery for renal cell carcinoma of 4 cm or less were reviewed retrospectively. Patients in group 1 underwent open retroperitoneal surgery (1998 to 2000) and patients in group 2 underwent laparoscopic (transperitoneal or retro peritoneal) surgery (2001 to March 2004). A single pathologist was employed to analyze the specimens, and comparative analysis included examination of tumor size, weight, histological cell type, intraoperative histological biopsies and margin status. Results: The 2 groups were comparable in terms of clinical data, and mean lesion size was 31.4 mm in group 1 and 32 mm in group 2. Positive margins were found in 1 of 30 patients in group 1 and in 1 of 34 in group 2 (p = 0.9). An analysis of margins was performed by taking measurements at the minimum and maximum points of the section. The minimum mean measurement was 2 mm in group 1 and 2.08 mm in group 2 (p = 0.75). The maximum mean measurement was 4.56 mm in group 1 and 5.2 mm in group 2 (p = 0.09). The difference between minimum and maximum margin thickness was 2.56 mm in group 1 and 3.16 mm in group 2 (p = 0.04). Mean followup for group 1 was 50 months (range 30 to 72) and 16 months (range 2 to 35) for group 2. One local recurrence was recorded in group 1 and treated with radical nephrectomy, while no recurrence was recorded in group 2. Conclusions: In this study we further confirmed the efficiency of resectioning lesions using laparoscopy. In our experience there is no difference between the 2 procedures in terms of efficient surgical margins. However, despite these encouraging results it is necessary to obtain more extensive followup data, which will allow us to be more specific in reporting on laparoscopic margin quality. References 1 : Nephron sparing surgery for renal tumors: indications, techniques and outcomes. J Urol2001; 166: 6. 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Link, Google Scholar From the Divisions of Urology and Pathology (EB), University of Turin−“San Luigi” Hospital, Orbassano and Division of Urology II (CF, DF), University of Turin−“San Giovanni Battista” Hospital, Turin, Italy© 2005 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byBreda A, Stepanian S, Liao J, Lam J, Guazzoni G, Stifelman M, Perry K, Celia A, Breda G, Fornara P, Jackman S, Rosales A, Palou J, Grasso M, Pansadoro V, Disanto V, Porpiglia F, Milani C, Abbou C, Gaston R, Janetschek G, Soomro N, de la Rosette J, Laguna M and Schulam P (2018) Positive Margins in Laparoscopic Partial Nephrectomy in 855 Cases: A Multi-Institutional Survey From the United States and EuropeJournal of Urology, VOL. 178, NO. 1, (47-50), Online publication date: 1-Jul-2007.Permpongkosol S, Colombo J, Gill I and Kavoussi L (2018) Positive Surgical Parenchymal Margin After Laparoscopic Partial Nephrectomy for Renal Cell Carcinoma: Oncological OutcomesJournal of Urology, VOL. 176, NO. 6, (2401-2404), Online publication date: 1-Dec-2006. Volume 173Issue 4April 2005Page: 1098-1101 Advertisement Copyright & Permissions© 2005 by American Urological Association, Inc.Keywordsnephron, laparoscopycarcinoma, renal cellMetricsAuthor Information FRANCESCO PORPIGLIA More articles by this author CRISTIAN FIORI More articles by this author CARLO TERRONE More articles by this author ENRICO BOLLITO More articles by this author DARIO FONTANA More articles by this author ROBERTO MARIO SCARPA More articles by this author Expand All Advertisement PDF downloadLoading ...