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<p>Refractory Kawasaki disease: diagnostic and management challenges</p>

2019; Dove Medical Press; Volume: Volume 10; Linguagem: Inglês

10.2147/phmt.s165935

1179-9927

Sophie Duignan, Sarah Doyle, Colin J. McMahon,

Vasculitis and related conditions

Abstract: Kawasaki disease (KD), an acute, self-limiting, medium-sized arterial vasculitis, is now the most common cause of acquired heart disease in childhood in the developed world. In this review, we discuss the diagnosis of KD, predicting resistance to traditional therapy and treatment options in refractory or high-risk disease. We also highlight ongoing clinical trials and other potential avenues of research which may prove beneficial in managing children, especially those with resistant KD. Keywords: aneurysm, arteritis, coronary, inflammation, Kawasaki, vasculitis