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Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District

2019; American Society of Tropical Medicine and Hygiene; Volume: 101; Issue: 6 Linguagem: Inglês

10.4269/ajtmh.19-0562

1476-1645

Sekeleghe A. Kayuni, E. James LaCourse, Peter Makaula, Fanuel Lampiao, Lazarus Juziwelo, Joanna Fawcett, Alexandra Shaw, Mohammad Alharbi, Jaco J. Verweij, J. Russell Stothard,

Parasite Biology and Host Interactions

Urogenital schistosomiasis causes morbidity within the genitalia but is underreported and infrequently examined in men. To draw attention to male genital schistosomiasis (MGS), a longitudinal cohort study was conducted among fishermen along the southwestern shoreline of Lake Malawi. A case series of five participants is presented inclusive of questionnaire interviews, parasitological examinations, ultrasonography, and provision of a standard dose (40 mg/kg) of praziquantel (PZQ) treatment at baseline, 1-, 3-, 6-, and 12-month follow-up time points. Eggs of Schistosoma haematobium were observed in urine or semen across all time points; parasitological diagnostics were bolstered by real-time PCR for Schistosoma DNA in semen and by portable ultrasonography to document putative MGS-associated morbidity. We highlight the importance of developing standard diagnostic tests for MGS and increasing the accessibility of PZQ treatment to men, especially those in at-risk endemic areas.