Portal de Periódicos da CAPES

Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing Human Immunodeficiency Virus (HIV)-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants

2019; Oxford University Press; Volume: 222; Issue: 4 Linguagem: Inglês

10.1093/infdis/jiz532

1537-6613

Coleen K. Cunningham, Elizabeth J. McFarland, R. L. Morrison, Edmund V. Capparelli, Jeffrey T. Safrit, Lynne Mofenson, Bonnie J. Mathieson, Megan Valentine, Charlotte Perlowski, Betsy Smith, Rohan Hazra, Lynette Purdue, Petronella Muresan, Paul A. Harding, Tapiwa Mbengeranwa, Lisa-Gaye Robinson, Andrew Wiznia, Gerhard Theron, Bob C. Lin, Robert T. Bailer, John R. Mascola, Barney S. Graham, Grace M. Aldrovandi, Frederic Bone, Dale Dayton, Benjamin Johnston, Patricia Morgan, Kathryn Myers, Nicole H. Tobin, Bonnie Zimmer, Magdel Rossouw, Lindie Rossouw, Jeanne Louw, Joanna Dobroszycki, Marlene Burey, Raphaelle Auguste, Kathleen K. Graham, Hanna Major‐Wilson, Tsungai Mhembere, Sukunena Maturure, Mutsa Bwakura‐Dangarembizi, Emily Barr, Jennifer Dunn, Carrie Glenny, Carrie Chambers, Mahboobullah Mirza Baig, Murli Purswani, Jaime Deville, Karin Nielsen‐Saines, Christina Shin, Michele F Carter, Ann Chahroudi, A. Ahonen, Martina L. Badell, Rana Chakraborty, Allison L. Agwu, W. Christopher Golden, Thuy Anderson, Aleisha Collinson-Streng, Rodrigo Diaz-Velasco, Nicolas Rosario, Elvia Pérez, Wanda I Marrero, Irma Febo, Ruth Santos, Carmen Zorrilla,

Cytomegalovirus and herpesvirus research

Although mother-to-child human immunodeficiency virus (HIV) transmission has dramatically decreased with maternal antiretroviral therapy, breast milk transmission accounts for most of the 180 000 new infant HIV infections annually. Broadly neutralizing antibodies (bNAb) may further reduce transmission.