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30-Year Trends in Serum Lipids Among United States Adults: Results from the National Health and Nutrition Examination Surveys II, III, and 1999–2006

2011; Elsevier BV; Volume: 107; Issue: 12 Linguagem: Inglês

10.1016/j.amjcard.2011.03.047

1879-1913

Margaret D. Carroll, David A. Lacher, Michael Wolz, Paul D. Sorlie,

Lipid metabolism and disorders

We have several concerns related to the report "30-Year Trends in Serum Lipids Among United States Adults: Results from the National Health and Nutrition Examination Surveys II, III, and 1999–2006" by Cohen et al.1 Our major concern involves the conclusions presented in this report regarding trends in serum triglyceride and in high-density lipoprotein (HDL) cholesterol in adults from 1976 to 2006 and their clinical implications. We are concerned about the validity of the statistical techniques on which the conclusions concerning trends in serum triglyceride are based and the effect of a method change in HDL cholesterol between 1999 to 2002 and 2003 to 2006 on trends in HDL cholesterol, both of which could alter the conclusions regarding these 2 lipid fractions presented by Cohen et al.