Portal de Periódicos da CAPES

Plant Reactome: a knowledgebase and resource for comparative pathway analysis

2019; Oxford University Press; Linguagem: Inglês

10.1093/nar/gkz996

1362-4962

Sushma Naithani, Parul Gupta, Justin Preece, Peter D’Eustachio, Justin Elser, Priyanka Garg, Daemon Dikeman, Jason Kiff, Justin Cook, Andrew Olson, Sharon Wei, Marcela K. Tello‐Ruiz, Antonio Fabregat, Alfonso Muñoz-Pomer Fuentes, Suhaib Mohammed, Tiejun Cheng, Evan Bolton, Irene Papatheodorou, Lincoln Stein, Doreen Ware, Pankaj Jaiswal,

Microbial Metabolic Engineering and Bioproduction

Abstract Plant Reactome (https://plantreactome.gramene.org) is an open-source, comparative plant pathway knowledgebase of the Gramene project. It uses Oryza sativa (rice) as a reference species for manual curation of pathways and extends pathway knowledge to another 82 plant species via gene-orthology projection using the Reactome data model and framework. It currently hosts 298 reference pathways, including metabolic and transport pathways, transcriptional networks, hormone signaling pathways, and plant developmental processes. In addition to browsing plant pathways, users can upload and analyze their omics data, such as the gene-expression data, and overlay curated or experimental gene-gene interaction data to extend pathway knowledge. The curation team actively engages researchers and students on gene and pathway curation by offering workshops and online tutorials. The Plant Reactome supports, implements and collaborates with the wider community to make data and tools related to genes, genomes, and pathways Findable, Accessible, Interoperable and Re-usable (FAIR).