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Humoral Factors From Musculoskeletal Polytrauma Patients Impair Antibacterial Responses Of Neutrophils In vitro

2019; Volume: 4; Issue: 6 Linguagem: Inglês

10.7150/jbji.35424

2206-3552

Aikaterini Stylianaki, Barbara Stanić, Mario Morgenstern, Geoff Richards, F Moriarty, Keith Thompson,

Total Knee Arthroplasty Outcomes

Polytrauma is associated with increased risk of sepsis, but the risk for implant infection is less clear. Neutrophil antibacterial responses are significantly reduced in polytrauma patients (n= 9, ISS≥15) for at least 5 days compared to healthy controls. Reduced neutrophil activity could influence implant infection in addition to sepsis.