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Sustainable, cost-efficient manufacturing of therapeutic peptides using chemo-enzymatic peptide synthesis (CEPS)

2019; Royal Society of Chemistry; Volume: 21; Issue: 23 Linguagem: Inglês

10.1039/c9gc03600h

1463-9270

Jan Pawlas, Timo Nuijens, Jonas Persson, Thomas Svensson, Marcel Schmidt, Ana Toplak, Mikael Nilsson, Jon H. Rasmussen,

Protein Hydrolysis and Bioactive Peptides

Exemplified by antidiabetic exenatide CEPS provides a highly efficient, easily scalable biocatalytic route to manufacture therapeutic peptides.