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A case of CD5-positive diffuse large B-cell lymphoma (DLBCL) presenting with the swelling of the mandibular gingiva as an initial symptom

2019; Japanese Society of Oral and Maxillofacial Surgeons; Volume: 65; Issue: 9 Linguagem: Inglês

10.5794/jjoms.65.582

2186-1579

Isao Miyamoto, Tomoyoshi Koyama, Yasushi Kimura, Shou Ishida, Toshikazu Takahara, Hideki Tanzawa,

Viral-associated cancers and disorders

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. The T-cell marker CD5 is positive in 5% to 10% of cases of DLBCL. We describe a rare case of CD5-positive DLBCL presenting with swelling of the mandibular gingiva. The patient was a 78-year-old-woman with a chief complaint of swelling of the mandibular gingiva. Biopsy was performed, and the patient was given a diagnosis of DLBCL. Moreover, analysis of the immunophenotype demonstrated that the lymphoma cells expressed CD5. The final diagnosis was CD5-positive DLBCL. The patient was treated with R-CHOP. There have been no signs of recurrence after the chemotherapy.