
Biomedical Applications: Gram‐Negative Bacteria Targeting Mediated by Carbohydrate–Carbohydrate Interactions Induced by Surface‐Modified Nanoparticles (Adv. Funct. Mater. 48/2019)
2019; Wiley; Volume: 29; Issue: 48 Linguagem: Inglês
10.1002/adfm.201970325
ISSN1616-3028
AutoresLarissa Brentano Capeletti, Jessica Fernanda Affonso de Oliveira, Lívia Mesquita Dias Loiola, Flávia Elisa Galdino, Denys E. S. Santos, Thereza A. Soares, Raul O. Freitas, Mateus Borba Cardoso,
Tópico(s)Enzyme Production and Characterization
ResumoIn article number 1904216, Mateus Borba Cardoso and co-workers demonstrate that nanoparticles fuctionalized with gluconamide moieties present selective targeting ability to Gram-negative bacteria membranes and no significant toxicity to mammalian or red blood cells. In addition, gluconamide functionality also provides tunable antibiotic delivery abilities, high stability in complex biological media, and lack of non-specific protein adhesion.
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