Portal de Periódicos da CAPES

The clinical implications of selective IgA deficiency

2019; Elsevier BV; Volume: 2; Linguagem: Inglês

10.1016/j.jtauto.2019.100025

2589-9090

Samantha Swain, Carlo Selmi, M. Eric Gershwin, Suzanne S. Teuber,

Adolescent and Pediatric Healthcare

Selective IgA deficiency (SIgAD) is the most common primary immunodeficiency but does not always result in clinical disease. This may in part be due to the definition based on serum IgA, while most IgA is secreted at mucosal surfaces, not amenable to measurement. Clinical complications include increased risk of sinopulmonary infections with bacteria and viruses, gastrointestinal infections with a predilection for