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BIBTEX RIS

In vitro activity of essential oils against adult and immature stages of Ctenocephalides felis felis

2019; Cambridge University Press; Volume: 147; Issue: 3 Linguagem: Inglês

10.1017/s0031182019001641

1469-8161

João Vitor Barbosa dos Santos, Douglas Siqueira de Almeida Chaves, Marco André Alves de Souza, Cristiano Jorge Riger, Monique Moraes Lambert, Diefrey Ribeiro Campos, Leandra Oliveira Moreira, Rosiane Conceição dos Santos Siqueira, Rodrigo de Paulo Osorio, Fábio Boylan, Thaís Ribeiro Correia, Katherina Coumendouros, Yara Peluso Cid,

Insect and Pesticide Research

Essential oils (EOs) are considered a new class of ecological products aimed at the control of insects for industrial and domestic use; however, there still is a lack of studies involving the control of fleas. Ctenocephalides felis felis, the most observed parasite in dogs and cats, is associated with several diseases. The aim of this study was to evaluate the in vitro activity, the establishment of LC50 and toxicity of EOs from Alpinia zerumbet (Pers.) B. L. Burtt & R. M. Sm, Cinnamomum spp., Laurus nobilis L., Mentha spicata L., Ocimum gratissimum L. and Cymbopogon nardus (L.) Rendle against immature stages and adults of C. felis felis. Bioassay results suggest that the method of evaluation was able to perform a pre-screening of the activity of several EOs, including the discriminatory evaluation of flea stages by their LC50. Ocimum gratissimum EO was the most effective in the in vitro assays against all flea stages, presenting adulticide (LC50 = 5.85 μg cm-2), ovicidal (LC50 = 1.79 μg cm-2) and larvicidal (LC50 = 1.21 μg cm-2) mortality at low doses. It also presented an excellent profile in a toxicological eukaryotic model. These findings may support studies involving the development of non-toxic products for the control of fleas in dogs and cats.