Artigo Acesso aberto Produção Nacional Revisado por pares

Continuous-flow synthesis of dimethyl fumarate: a powerful small molecule for the treatment of psoriasis and multiple sclerosis

2020; Royal Society of Chemistry; Volume: 10; Issue: 5 Linguagem: Inglês

10.1039/c9ra09119j

ISSN

2046-2069

Autores

Marcelo T. Lima, Fernanda G. Finelli, Alline V. B. de Oliveira, Vinícius Kartnaller, João Cajaiba, Raquel A. C. Leão, Rodrigo O. M. A. de Souza,

Tópico(s)

Click Chemistry and Applications

Resumo

Dimethyl fumarate (DMF) has recently gained attention due to its use as a pro-drug in different pharmaceutical preparations, here in we present our work on a cascade methodology in short reaction times and quantitative yields.

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