
Continuous-flow synthesis of dimethyl fumarate: a powerful small molecule for the treatment of psoriasis and multiple sclerosis
2020; Royal Society of Chemistry; Volume: 10; Issue: 5 Linguagem: Inglês
10.1039/c9ra09119j
ISSN2046-2069
AutoresMarcelo T. Lima, Fernanda G. Finelli, Alline V. B. de Oliveira, Vinícius Kartnaller, João Cajaiba, Raquel A. C. Leão, Rodrigo O. M. A. de Souza,
Tópico(s)Click Chemistry and Applications
ResumoDimethyl fumarate (DMF) has recently gained attention due to its use as a pro-drug in different pharmaceutical preparations, here in we present our work on a cascade methodology in short reaction times and quantitative yields.
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