Portal de Periódicos da CAPES

Synthesis, characterization, antimicrobial activities and electrochemical behavior of new phenolic azo dyes from two thienocoumarin amines

2019; ARKAT USA, Inc.; Volume: 2019; Issue: 6 Linguagem: Inglês

10.24820/ark.5550190.p010.994

1551-7012

Kamal S. D. Djeukoua, Emmanuel Sopbué Fondjo, Jean‐De‐Dieu Tamokou, Joseph Tsemeugne, Peter F. W. Simon, Appolinaire Tsopmo, Francis Merlin Melataguia Tchieno, Steve Endeguele Ekom, Chancellin Nkepdep Pecheu, Ignas Kenfack Tonlé, Jules-Roger Kuiateb,

Synthesis and Biological Evaluation

The coupling reactions of diazotized thienocoumarin derivatives with p-acetaminophen, salicylic acid and acetylsalicylic acid gave four products in which the benzene ring of the phenolic reagents were primarily substituted by two 3-diazenyl-4H-thieno[3,4-c]chromen-4-one or 3-diazenyl-4-imino-4H-thieno[3,4c]chromene moieties.The newly prepared azo dyes were fully characterized based on their analytical and spectroscopic data.The electrochemical analysis of the novel azo dyes carried out on a glassy carbon electrode unequivocally further confirmed the assigned structures.The synthesized compounds tested for their antimicrobial activity using broth microdilution method, showed good activities.