Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation
2020; Lippincott Williams & Wilkins; Volume: 38; Issue: 13 Linguagem: Inglês
10.1200/jco.19.02931
ISSN1527-7755
AutoresEileen M. O’Reilly, Jonathan W. Lee, Mark M. Zalupski, Marinela Capanu, Jennifer Park, Talia Golan, Esther Tahover, Maeve A. Lowery, Joanne F. Chou, Vaibhav Sahai, Robin Brenner, Hedy L. Kindler, Kenneth H. Yu, Alice Zervoudakis, Shreya Vemuri, Zsofia K. Stadler, Richard Kinh Gian, Neesha C. Dhani, Alice Chen, David P. Kelsen,
Tópico(s)PARP inhibition in cancer therapy
ResumoFive percent to 9% of pancreatic ductal adenocarcinomas (PDACs) develop in patients with a germline
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